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Departments / Cancer Biology / Breast Cancer Research Program / Breast Cancer Research Resources

Breast Cancer Research Program (BCRP) Research Resources

Our breast cancer research program currently has the following research resources available for the breast cancer research community with more to come, thanks to the generous support from the University of Cincinnati Cancer Center, Ride Cincinnati Foundation, and Waddell Family Fund. You may request these samples from the UCCC Biospecimen Shared Resource following the standard sample request procedure. Best wishes for your research and please acknowledge the above support in your presentation and publication when appropriate.

Patient-Derived Organoid (PDO) models:

PDO Model ID Specimen ID Cancer type Diagnosis Subtype PDO Media Notes Funding Sources
UCBCRP-PDO001MAL1527-TU1-PDO IDC ER-, PR-, HER2 Moderate M1 UCCC, Ride Cincinnati
UCBCRP-PDO002MAL1409-TU1-PDOLDC ER+, PR+, HER2(2+ with Amp) M1IHC Confirmed Subtype of PDO Tumor UCCC, Ride Cincinnati
UCBCRP-PDO003 MAL1590-TU1-PDO IDC, focal lobular features ER+, PR+, HER2- M2IHC Confirmed Subtype of PDO Tumor UCCC, Ride Cincinnati
UCBCRP-PDO004 MAL1592-TU1-PDO Squamous Cell carcinoma, keratinizing ER-, PR-, HER2- M1IHC Confirmed Subtype of PDO Tumor UCCC, Ride Cincinnati, Waddell Family Fund
UCBCRP-PDO005 MAL1670-TU1-PDOInvasive Carcinoma ER+, PR+, HER2- M2  UCCC, Ride Cincinnati
UCBCRP-PDO006 MAL1671-TU1-PDO Mucinous carcinoma ER+, PR+, HER2- M2  UCCC, Ride Cincinnati
UCBCRP-PDO007 MAL1772-TU1-PDO IDC ER+, PR+, HER2- M2  UCCC, Ride Cincinnati

Patient-Derived Xenograft (PDX) Model:

PDO Model ID Specimen ID Cancer type Diagnosis Subtype PDO Media Notes Funding Sources
UCBCRP-PDX001 MAL1527 -TU1-PDXIDC ER-, PR-, HER2 Moderate M1IHC Confirmed Subtype of PDX Tumor UCCC, Ride Cincinnati

Normal breast tissue (NBT) PDOs:

PDO Model ID Specimen ID PDO Media Notes Funding Sources
UCBCRP-NBT001 MAL1527-NO1-PDO M2Matched with UCBCRP-PDX001 and UCBCRP-PDO001 UCCC, Ride Cincinnati
UCBCRP-NBT002MAL1590 -NO1-PDO M2Matched with UCBCRP-PDO003 UCCC, Ride Cincinnati
UCBCRP-NBT003 MAL1579 -NO1-PDO M2 UCCC, Ride Cincinnati
UCBCRP-NBT004 MAL1671 -NO1-PDO M2Matched with UCBCRP-PDO006 UCCC, Ride Cincinnati, Waddell Family Fund
UCBCRP-NBT005 MAL1765 -NO1-PDO M2 Matched tumor PDO is slow growing but will become available UCCC, Ride Cincinnati

Protocols:

BCRP PDX protocol 0923 (pdf)

BCRP PDO Protocol 0923 (pdf)

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Department of Cancer Biology

Vontz Center for Molecular Studies
3125 Eden Avenue
PO Box 670521
Cincinnati, OH 45267-0521

Mail Location: 0521
Phone: 513-558-5323
Fax: 513-558-1190
Email: cbrecruitment@uc.edu