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Erik B. Nelson, MD

Professor of Clinical

Psychiatry & Behavioral Neuroscience | College of Medicine

Education/Credentials
  • Medical Degree: University of Cincinnati College of Medicine
  • Residency: University of Cincinnati/University Hospital (General Psychiatry)
Board Certifications & Licenses

American Board of Psychiatry and Neurology (Psychiatry) (Certification Date: 1997-11-17) - (Recertification Date: 2019-08-19)

Specialties

Psychiatry

Contact Information

Clinical Interests

Psychiatry

Major Depressive Disorder

Treatment Resistant Depression

Mood Disorders

Peer Reviewed Publications

Guidetti, Clotilde; Chaikali, Stefania; Trivedi, Madhukar H; Shelton, Richard C; Iosifescu, Dan V; Thase, Michael E; Jha, Manish K; Mathew, Sanjay H; DeBattista, Charles; Dokucu, Mehmet E; Brawman-Mintzer, Olga; Hernández Ortiz, Jesús Manuel; Currier, Glenn W; McCall, William Vaughn; Modirrousta, Mandana; Macaluso, Matthew; Bystritsky, Alexander; Vila-Rodriguez, Fidel; Nelson, Erik B; Yeung, Albert S; MacGregor, Leslie C; Carmody, Thomas; Fava, Maurizio; Papakostas, George I 2025. Comparative Effectiveness Research Trial for Antidepressant Incomplete and Nonresponders With Treatment Resistant Depression (ASCERTAIN-TRD): Effect of Aripiprazole or Repetitive Transcranial Magnetic Stimulation Augmentation Versus Switching to the Antidepressant Venlafaxine on Quality of Life. The Journal of clinical psychiatry, 86 3,

Guidetti, Clotilde; Chaikali, Stefania; Trivedi, Madhukar H; Shelton, Richard C; Iosifescu, Dan V; Thase, Michael E; Jha, Manish K; Mathew, Sanjay J; DeBattista, Charles; Dokucu, Mehmet E; Brawman-Mintzer, Olga; Ortiz, Jesús Manuel Hernández; Currier, Glenn W; McCall, William Vaughn; Modirrousta, Mandana; Macaluso, Matthew; Bystritsky, Alexander; Vila-Rodriguez, Fidel; Nelson, Erik B; Yeung, Albert S; MacGregor, Leslie C; Carmody, Thomas; Fava, Maurizio; Papakostas, George I 2025. Effect of augmentation with aripiprazole or augmentation with repetitive transcranial magnetic stimulation versus switching to the antidepressant venlafaxine extended release/duloxetine on cognition: A comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment-resistant depression (ASCERTAIN-TRD). Journal of affective disorders, 390 , 119836

Murata, Stephen A; Madaj, Zachary B; Capan, Colt D; Sheldon, Ryan D; El-Mallakh, Rif S; Parikh, Sagar V; Bobo, William V; Goes, Fernando S; Wolkowitz, Owen M; Vande Voort, Jennifer L; Nykamp, Louis J; Singh, Balwinder; Medeiros, Gustavo C; Nelson, Erik B; Thase, Michael E; Oxenkrug, Gregory F; Frye, Mark A; Greden, John F; Achtyes, Eric D; Brundin, Lena C 2025. High Baseline Plasma Anthranilic Acid Predicts Remission Upon Acute-Series Ketamine Infusion for Treatment-Resistant Depression. Biological psychiatry global open science, 5 4, 100503

Papakostas, George I; Trivedi, Madhukar H; Shelton, Richard C; Iosifescu, Dan V; Thase, Michael E; Jha, Manish K; Mathew, Sanjay J; DeBattista, Charles; Dokucu, Mehmet E; Brawman-Mintzer, Olga; Currier, Glenn W; McCall, William Vaughn; Modirrousta, Mandana; Macaluso, Matthew; Bystritsky, Alexander; Rodriguez, Fidel Vila; Nelson, Erik B; Yeung, Albert S; Feeney, Anna; MacGregor, Leslie C; Carmody, Thomas; Fava, Maurizio 2024. Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a randomized clinical trial. Molecular psychiatry, 29 8, 2287-2295

Kustubayeva, Almira M; Nelson, Erik B; Smith, Michael L; Allendorfer, Jane B; Eliassen, James C 2023. Corrigendum: Functional MRI study of feedback-based reinforcement learning in depression. Frontiers in neuroinformatics, 17 , 1175847

Kustubayeva, Almira; Eliassen, James; Matthews, Gerald; Nelson, Erik 2023. FMRI study of implicit emotional face processing in patients with MDD with melancholic subtype. Frontiers in human neuroscience, 17 , 1029789

Kustubayeva, Almira M; Nelson, Erik B; Smith, Michael L; Allendorfer, Jane B; Eliassen, James C 2022. Functional MRI study of feedback-based reinforcement learning in depression. Frontiers in neuroinformatics, 16 , 1028121

Parker, Christopher; Nelson, Erik; Zhang, Tongli 2022. VeVaPy, a Python Platform for Efficient Verification and Validation of Systems Biology Models with Demonstrations Using Hypothalamic-Pituitary-Adrenal Axis Models. Entropy (Basel, Switzerland), 24 12,

Goodman, Adam M; Allendorfer, Jane B; Heyse, Heidi; Szaflarski, Basia A; Eliassen, James C; Nelson, Erik B; Storrs, Judd M; Szaflarski, Jerzy P 2019. Neural response to stress and perceived stress differ in patients with left temporal lobe epilepsy. Human brain mapping, 40 12, 3415-3430

Wade, Natasha E; Padula, Claudia B; Anthenelli, Robert M; Nelson, Erik; Eliassen, James; Lisdahl, Krista M 2017. Blunted amygdala functional connectivity during a stress task in alcohol dependent individuals: A pilot study. Neurobiology of stress, 7 , 74-79

Padula, Claudia B; Anthenelli, Robert M; Eliassen, James C; Nelson, Erik; Lisdahl, Krista M 2015. Gender effects in alcohol dependence: an fMRI pilot study examining affective processing. Alcoholism, clinical and experimental research, 39 2, 272-81

Allendorfer, Jane B; Heyse, Heidi; Mendoza, Lucy; Nelson, Erik B; Eliassen, James C; Storrs, Judd M; Szaflarski, Jerzy P 2014. Physiologic and cortical response to acute psychosocial stress in left temporal lobe epilepsy - a pilot cross-sectional fMRI study. Epilepsy & behavior : E&B, 36 , 115-23

Cerullo, Michael A; Eliassen, James C; Smith, Christopher T; Fleck, David E; Nelson, Erik B; Strawn, Jeffrey R; Lamy, Martine; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2014. Bipolar I disorder and major depressive disorder show similar brain activation during depression. Bipolar disorders, ,

Guerdjikova, Anna I; McElroy, Susan L; Winstanley, Erin L; Nelson, Eric B; Mori, Nicole; McCoy, Jessica; Keck, Paul E; Hudson, James I 2012. Duloxetine in the treatment of binge eating disorder with depressive disorders: a placebo-controlled trial. The International journal of eating disorders, 45 2, 281-9

Nelson, Erik B 2012. Psychotic depression--beyond the antidepressant/antipsychotic combination. Current psychiatry reports, 14 6, 619-23

Papakostas, George I; Shelton, Richard C; Zajecka, John M; Etemad, Bijan; Rickels, Karl; Clain, Alisabet; Baer, Lee; Dalton, Elizabeth D; Sacco, Garret R; Schoenfeld, David; Pencina, Michael; Meisner, Allison; Bottiglieri, Teodoro; Nelson, Erik; Mischoulon, David; Alpert, Jonathan E; Barbee, James G; Zisook, Sidney; Fava, Maurizio 2012. L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials. The American journal of psychiatry, 169 12, 1267-74

Guerdjikova, Anna I; McElroy, Susan L; Welge, Jeffrey A; Nelson, Erik; Keck, Paul E; Hudson, James I 2009. Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial. International clinical psychopharmacology, 24 3, 150-8

Guerdjikova, Anna I; McElroy, Susan L; Kotwal, Renu; Welge, Jeffrey A; Nelson, Erik; Lake, Katie; Alessio, David D 2008. High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trial. Human psychopharmacology, 23 1, 1-11

McElroy, Susan L; Nelson, Erik B; Welge, Jeffrey A; Kaehler, Laura; Keck, Paul E 2008. Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial. The Journal of clinical psychiatry, 69 3, 433-40

McElroy, Susan L; Guerdjikova, Anna; Kotwal, Renu; Welge, Jeffrey A; Nelson, Erik B; Lake, Kathleen A; Keck, Paul E; Hudson, James I 2007. Atomoxetine in the treatment of binge-eating disorder: a randomized placebo-controlled trial. The Journal of clinical psychiatry, 68 3, 390-8

DelBello, Melissa P; Kowatch, Robert A; Adler, Caleb M; Stanford, Kevin E; Welge, Jeffrey A; Barzman, Drew H; Nelson, Erik; Strakowski, Stephen M 2006. A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania. Journal of the American Academy of Child and Adolescent Psychiatry, 45 3, 305-13

DelBello, Melissa P; Kowatch, Robert A; Adler, Caleb M; Stanford, Kevin E; Welge, Jeffrey A; Barzman, Drew H; Nelson, Erik; Strakowski, Stephen M 2006. A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania. Journal of the American Academy of Child and Adolescent Psychiatry, 45 3, 305-13

McElroy, Susan L; Kotwal, Renu; Guerdjikova, Anna I; Welge, Jeffrey A; Nelson, Erik B; Lake, Kathleen A; D 2006. Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trial. The Journal of clinical psychiatry, 67 12, 1897-906

Dunsieth, Neal W; Nelson, Erik B; Brusman-Lovins, Lori A; Holcomb, Jeff L; Beckman, DeAnna; Welge, Jeffrey A; Roby, David; Taylor, Purcell; Soutullo, Cesar A; McElroy, Susan L 2004. Psychiatric and legal features of 113 men convicted of sexual offenses. The Journal of clinical psychiatry, 65 3, 293-300

Dunsieth, Neal W; Nelson, Erik B; Brusman-Lovins, Lori A; Holcomb, Jeff L; Beckman, DeAnna; Welge, Jeffrey A; Roby, David; Taylor, Purcell; Soutullo, Cesar A; McElroy, Susan L 2004. Psychiatric and legal features of 113 men convicted of sexual offenses. The Journal of clinical psychiatry, 65 3, 293-300

McElroy, Susan L; Kotwal, Renu; Hudson, James I; Nelson, Erik B; Keck, Paul E 2004. Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trial. The Journal of clinical psychiatry, 65 1, 50-6

McElroy, Susan L; Kotwal, Renu; Malhotra, Shishuka; Nelson, Erik B; Keck, Paul E; Nemeroff, Charles B 2004. Are mood disorders and obesity related? A review for the mental health professional. The Journal of clinical psychiatry, 65 5, 634-51, quiz 730

Keck, Paul E; Nelson, Erik B; McElroy, Susan L 2003. Advances in the pharmacologic treatment of bipolar depression. Biological psychiatry, 53 8, 671-9

McElroy, Susan L; Hudson, James I; Malhotra, Shishuka; Welge, Jeffrey A; Nelson, Erik B; Keck, Paul E 2003. Citalopram in the treatment of binge-eating disorder: a placebo-controlled trial. The Journal of clinical psychiatry, 64 7, 807-13

Nelson, E B; Rielage, E; Welge, J A; Keck, P E 2001. An open trial of olanzapine in the treatment of patients with psychotic depression. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 13 3, 147-51

Nelson, E B; Shah, V N; Welge, J A; Keck, P E 2001. A placebo-controlled, crossover trial of granisetron in SRI-induced sexual dysfunction. The Journal of clinical psychiatry, 62 6, 469-73

Nelson, E; Brusman, L; Holcomb, J; Soutullo, C; Beckman, D; Welge, J A; Kuppili, N; McElroy, S L 2001. Divalproex sodium in sex offenders with bipolar disorders and comorbid paraphilias: an open retrospective study. Journal of affective disorders, 64 2-3, 249-55

McElroy, S L; Casuto, L S; Nelson, E B; Lake, K A; Soutullo, C A; Keck, P E; Hudson, J I 2000. Placebo-controlled trial of sertraline in the treatment of binge eating disorder. The American journal of psychiatry, 157 6, 1004-6

McElroy, S L; Soutullo, C A; Taylor, P; Nelson, E B; Beckman, D A; Brusman, L A; Ombaba, J M; Strakowski, S M; Keck, P E 1999. Psychiatric features of 36 men convicted of sexual offenses. The Journal of clinical psychiatry, 60 6, 414-20; quiz 421-2

Nelson, E B; Sax, K W; Strakowski, S M 1998. Attentional performance in patients with psychotic and nonpsychotic major depression and schizophrenia. The American journal of psychiatry, 155 1, 137-9

Nelson, E B; Keck, P E; McElroy, S L 1997. Resolution of fluoxetine-induced sexual dysfunction with the 5-HT3 antagonist granisetron. The Journal of clinical psychiatry, 58 11, 496-7

Kustubayeva A.M.; Nelson E.B.; Smith M.L.; Allendorfer J.B.; Eliassen J.C. 12-20-2022. Functional MRI study of feedback-based reinforcement learning in depression Frontiers in Neuroinformatics, 16 ,

Parker C.; Nelson E.; Zhang T. 12-01-2022. VeVaPy, a Python Platform for Efficient Verification and Validation of Systems Biology Models with D Entropy, 24 12,

Wade N.; Padula C.; Anthenelli R.; Nelson E.; Eliassen J.; Lisdahl K. 12-01-2017. Blunted amygdala functional connectivity during a stress task in alcohol dependent individuals: A pi Neurobiology of Stress, 7 , 74-79

Papakostas G.I.; Shelton R.C.; Zajecka J.M.; Etemad B.; Rickels K.; Clain A.; Baer L.; Dalton E.D.; Sacco G.R.; Schoenfeld D.; Pencina M.; Meisner A.; Bottiglieri T.; Nelson E.; Mischoulon D.; Alpert J.E.; Barbee J.G.; Zisook S.; Fava M. 12-01-2012. L-methylfolate as adjunctive therapy for SSRI-resistant major depression: Results of two randomized, American Journal of Psychiatry, 169 12, 1267-1274

Herman J.P.; Figueiredo H.F.; Mueller N.K.; Ostrander M.M.; Zhang R.; Tauchi M.; Choi D.C.; Furay A.R.; Evanson N.K.; Nelson E.B.; Ulrich-Lai Y.M. 12-01-2007. Neurochemical systems regulating the hypothalamo-pituitary-adrenocortical axis Handbook of Neurochemistry and Molecular Neurobiology: Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology, , 513-569

Murata S.A.; Madaj Z.B.; Capan C.D.; Sheldon R.D.; El-Mallakh R.S.; Parikh S.V.; Bobo W.V.; Goes F.S.; Wolkowitz O.M.; Vande Voort J.L.; Nykamp L.J.; Singh B.; Medeiros G.C.; Nelson E.B.; Thase M.E.; Oxenkrug G.F.; Frye M.A.; Greden J.F.; Achtyes E.D.; Brundin L.C. 07-01-2025. High Baseline Plasma Anthranilic Acid Predicts Remission Upon Acute-Series Ketamine Infusion for Tre Biological Psychiatry Global Open Science, 5 4,

Parker C.; Nelson E.; Zhang T. 01-01-2024. Applying neural ordinary differential equations for analysis of hormone dynamics in Trier Social Str Frontiers in Genetics, 15 ,

Kustubayeva A.; Eliassen J.; Matthews G.; Nelson E. 01-01-2023. FMRI study of implicit emotional face processing in patients with MDD with melancholic subtype Frontiers in Human Neuroscience, 17 ,

Nelson E. 01-01-2008. Role of antiepileptic drugs in the treatment of major depressive disorder Antiepileptic Drugs to Treat Psychiatric Disorders, , 177-186

McElroy S.L.; Kotwal R.; Nelson E.B.; Malhotra S.; Keck P.E.; Nemeroff C.B. 01-01-2006. Obesity and Mood Disorders Obesity and Mental Disorders, , 41-92

Nelson E.; McElroy S. 01-01-1997. Psychotic depression: A guide to drug choice CNS Drugs, 8 6, 457-473