- Postdoctorate: Cincinnati Children’s Hospital Medical Center (Computational biology and bioinformatics)
- Doctoral Degree: Tver State University (Chemistry)
- Master: Mari State University (Chemistry)
- Email porollay@ucmail.uc.edu
My research lies at the intersection of computational biology, artificial intelligence, and biomedical data science, with a focus on developing computational methods to advance our understanding of protein structure and function, molecular interactions, and mechanisms of human disease. Building on my interdisciplinary background in chemistry, structural bioinformatics, and molecular biology, I have developed widely used methods and software tools for protein structure prediction, functional annotation, an...
Porollo, Aleksey; Jadhav, Om; Alvarez, Aaron; Chen, Jichao 2026. SPPIDER-seq: sequence-based partner-aware predictor of protein-protein interaction sites. Bioinformatics (Oxford, England), 42 7,
Albee, Aaron W; Sayson, Steven G; Ashbaugh, Alan; Wolf, Nicholas J; Porollo, Aleksey; Smulian, George; Cushion, Melanie T 2025. Single-cell RNA sequencing defines developmental progression and reproductive transitions of Pneumocystis carinii. Microbiology spectrum, 13 10, e0127725
Porollo, Aleksey; Sayson, Steven G; Ashbaugh, Alan; Rebholz, Sandra; Landero Figueroa, Julio A; Cushion, Melanie T 2024. Insights into copper sensing and tolerance in Pneumocystis species. Frontiers in microbiology, 15 , 1383737
Tran, Chau; Khadkikar, Siddharth; Porollo, Aleksey 2023. Survey of Protein Sequence Embedding Models. International journal of molecular sciences, 24 4,
Van Camp, Pieter-Jan; Prasath, V B Surya; Haslam, David B; Porollo, Aleksey 2023. MGS2AMR: a gene-centric mining of metagenomic sequencing data for pathogens and their antimicrobial resistance profile. Microbiome, 11 1, 223
Van Camp, Pieter-Jan; Haslam, David B; Porollo, Aleksey 2020. Prediction of Antimicrobial Resistance in Gram-Negative Bacteria From Whole-Genome Sequencing Data. Frontiers in microbiology, 11 , 1013
Baker, Frazier N; Porollo, Aleksey 2016. CoeViz: a web-based tool for coevolution analysis of protein residues. BMC bioinformatics, 17 , 119
Porollo, Aleksey; Sesterhenn, Thomas M; Collins, Margaret S; Welge, Jeffrey A; Cushion, Melanie T 2014. Comparative genomics of pneumocystis species suggests the absence of genes for myo-inositol synthesis and reliance on inositol transport and metabolism. mBio, 5 6, e01834
Syed K, Porollo A, Miller D, Yadav JS. 2013. Rational engineering of the fungal P450 monooxygenase CYP5136A3 to improve its oxidizing activity toward polycyclic aromatic hydrocarbons. Protein Eng Des Sel., 26 9, 553
Porollo, Aleksey; Meller, Jarosław 2007. Prediction-based fingerprints of protein-protein interactions. Proteins, 66 3, 630-45