Jialiang Liang

Peer Reviewed Publications

Dutta, Suchandrima; Chen, Sophie; Ahmad, Waqas; Huang, Wei; Liang, Jialiang; Wang, Yigang 2026. Targeting Cardiac Fibroblast Plasticity for Antifibrotic and Regenerative Therapy in Heart Failure. Cells, 15 2,

Dutta, Suchandrima; Chen, Sophie; Ahmad, Waqas; Huang, Wei; Wang, Yigang; Liang, Jialiang 2026. In vivo CRISPR-mediated activation of cardiogenic genes to reprogram cardiac fibroblasts. Frontiers in cell and developmental biology, 14 , 1812941

He, Xingyu; Dutta, Suchandrima; Desai, Darshini; Zhong, Sheng; Liu, William; Chen, Sophie; Huang, Wei; Ahmad, Waqas; Liang, Jialiang; Wang, Yigang 2026. Oxygen-generating Microparticles Enhance Viability and Functionality of Human Pluripotent Stem Cell-derived Cardiomyocytes for Myocardial Infarction Therapy. Stem cell reviews and reports, 22 6, 2846-2862

Ahmad, Waqas; Dutta, Suchandrima; He, Xingyu; Chen, Sophie; Saleem, Muhammad Zubair; Wang, Yigang; Liang, Jialiang 2025. In Vivo Targeted Reprogramming of Cardiac Fibroblasts for Heart Regeneration: Advances and Therapeutic Potential. Bioengineering (Basel, Switzerland), 12 9,

Dutta, Suchandrima; Chen, Sophie; He, Xingyu; Wang, Boyu; Wu, Zhichao; Ahmad, Waqas; Huang, Wei; Du, Wa; Fan, Yanbo; Liang, Jialiang; Wang, Yigang 2025. A clinical practice review: management strategies and emerging approaches for anastomotic leakage following radical surgery for esophageal cancer. Annals of palliative medicine, 14 5, 495-502

Wang, Boyu; He, Xingyu; Dutta, Suchandrima; Chen, Sophie; Liang, Jialiang; Huang, Wei; Ahmad, Waqas; Xu, Meifeng; Wang, Yigang 2025. New progress and challenges of targeted therapies for breast cancer. Annals of palliative medicine, 14 4, 345-352

Cai, Wen-Feng; Jiang, Lin; Liang, Jialiang; Dutta, Suchandrima; Huang, Wei; He, Xingyu; Wu, Zhichao; Paul, Christian; Gao, Xiang; Xu, Meifeng; Kanisicak, Onur; Zheng, Junmeng; Wang, Yigang 2024. HAX1-Overexpression Augments Cardioprotective Efficacy of Stem Cell-Based Therapy Through Mediating Hippo-Yap Signaling. Stem cell reviews and reports, 20 6, 1569-1586

He, Xingyu; Good, Angela; Kalou, Wael; Ahmad, Waqas; Dutta, Suchandrima; Chen, Sophie; Lin, Charles Noah; Chella Krishnan, Karthickeyan; Fan, Yanbo; Huang, Wei; Liang, Jialiang; Wang, Yigang 2024. Current Advances and Future Directions of Pluripotent Stem Cells-Derived Engineered Heart Tissue for Treatment of Cardiovascular Diseases. Cells, 13 24,

Liang, Jialiang; He, Xingyu; Wang, Yigang 2024. Cardiomyocyte proliferation and regeneration in congenital heart disease. Pediatric discovery, 2 3,

He, Xingyu; Dutta, Suchandrima; Liang, Jialiang; Paul, Christian; Huang, Wei; Xu, Meifeng; Chang, Vivian; Wang, Yigang 2023. Direct Cellular Reprogramming Techniques for Cardiovascular Regenerative Therapeutics. Canadian journal of physiology and pharmacology, ,

Park, Ki Ho; He, Xingyu; Jiang, Lin; Zhu, Hua; Liang, Jialiang; Wang, Yigang; Ma, Jianjie 2023. Activation of MG53 Enhances Cell Survival and Engraftment of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Injured Hearts. Stem cell reviews and reports, 19 7, 2420-2428

Wu, Zhichao; Huang, Wei; He, Xingyu; Dutta, Suchandrima; Paul, Christian; Fan, Guo-Chang; Kanisicak, Onur; Xu, Meifeng; Liang, Jialiang; Wang, Yigang 2023. Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury. bioRxiv : the preprint server for biology, ,

He, Xingyu; Liang, Jialiang; Paul, Christian; Huang, Wei; Dutta, Suchandrima; Wang, Yigang 2022. Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair. Cells, 11 23,

Jiang, Lin; Liang, Jialiang; Huang, Wei; Ma, Jianyong; Park, Ki Ho; Wu, Zhichao; Chen, Peng; Zhu, Hua; Ma, Jian-Jie; Cai, Wenfeng; Paul, Christian; Niu, Liang; Fan, Guo-Chang; Wang, Hong-Sheng; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2022. CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy. Molecular therapy : the journal of the American Society of Gene Therapy, 30 1, 54-74

Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Gao, Xiang; Alam, Perwez; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2021. Immunomodulatory effects of mesenchymal stem cells for the treatment of cardiac allograft rejection. Experimental biology and medicine (Maywood, N.J.), 246 7, 851-860

Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Lin, Bonnie; Zheng, Junmeng; Wang, Yigang 2021. Prompt Graft Cooling Enhances Cardioprotection during Heart Transplantation Procedures through the Regulation of Mitophagy. Cells, 10 11,

Jiang, Lin; Liang, Jialiang; Huang, Wei; Wu, Zhichao; Paul, Christian; Wang, Yigang 2020. Strategies and Challenges to Improve Cellular Programming-Based Approaches for Heart Regeneration Therapy. International journal of molecular sciences, 21 20,

Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Li, Xiangnan; Wang, Yigang 2019. Concise Review: Reduction of Adverse Cardiac Scarring Facilitates Pluripotent Stem Cell-Based Therapy for Myocardial Infarction. Stem cells (Dayton, Ohio), 37 7, 844-854

Huang, Wei; Feng, Yuliang; Liang, Jialiang; Yu, Hao; Wang, Cheng; Wang, Boyu; Wang, Mingyang; Jiang, Lin; Meng, Wei; Cai, Wenfeng; Medvedovic, Mario; Chen, Jenny; Paul, Christian; Davidson, W Sean; Sadayappan, Sakthivel; Stambrook, Peter J; Yu, Xi-Yong; Wang, Yigang 2018. Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration. Nature communications, 9 1, 700

Huang, Wei; Liang, Jialiang; Feng, Yuliang; Jia, Zhanfeng; Jiang, Lin; Cai, Wenfeng; Paul, Christian; Gu, Jianguo G; Stambrook, Peter J; Millard, Ronald W; Zhu, Xiao-Lan; Zhu, Ping; Wang, Yigang 2018. Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential. Experimental cell research, 371 1, 20-30

Ma, Ruilian; Liang, Jialiang; Huang, Wei; Guo, Linlin; Cai, Wenfeng; Wang, Lei; Paul, Christian; Yang, Huang-Tian; Kim, Ha Won; Wang, Yigang 2018. Electrical Stimulation Enhances Cardiac Differentiation of Human Induced Pluripotent Stem Cells for Myocardial Infarction Therapy. Antioxidants & redox signaling, 28 5, 371-384

Liang, Jialiang; Huang, Wei; Cai, Wenfeng; Wang, Lei; Guo, Linlin; Paul, Christian; Yu, Xi-Yong; Wang, Yigang 2017. Inhibition of microRNA-495 Enhances Therapeutic Angiogenesis of Human Induced Pluripotent Stem Cells. Stem cells (Dayton, Ohio), 35 2, 337-350

Cai, Wen-Feng; Kang, Kai; Huang, Wei; Liang, Jia-Liang; Feng, Yu-Liang; Liu, Guan-Sheng; Chang, De-Hua; Wen, Zhi-Li; Paul, Christian; Xu, Meifeng; Millard, Ronald W; Wang, Yigang 2015. CXCR4 attenuates cardiomyocytes mitochondrial dysfunction to resist ischaemia-reperfusion injury. Journal of cellular and molecular medicine, 19 8, 1825-35

Kang, Kai; Ma, Ruilian; Cai, Wenfeng; Huang, Wei; Paul, Christian; Liang, Jialiang; Wang, Yuhua; Zhao, Tiejun; Kim, Ha Won; Xu, Meifeng; Millard, Ronald W; Wen, Zhili; Wang, Yigang 2015. Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial Infarction. Stem cells international, 2015 , 659890

Wang, Yuhua; Huang, Wei; Liang, Jialiang; Wen, Zhili; Chang, Dehua; Kang, Kai; Wang, Jiapeng; Xu, Meifeng; Millard, Ronald W; Wang, Yigang 2014. Suicide gene-mediated sequencing ablation revealed the potential therapeutic mechanism of induced pluripotent stem cell-derived cardiovascular cell patch post-myocardial infarction. Antioxidants & redox signaling, 21 16, 2177-91

Wen, Zhili; Huang, Wei; Feng, Yuliang; Cai, Wenfeng; Wang, Yuhua; Wang, Xiaohong; Liang, Jialiang; Wani, Mashhood; Chen, Jing; Zhu, Pin; Chen, Ji-Mei; Millard, Ronald W; Fan, Guo-Chang; Wang, Yigang 2014. MicroRNA-377 regulates mesenchymal stem cell-induced angiogenesis in ischemic hearts by targeting VEGF. PloS one, 9 9, e104666

Liang, Jialiang; Huang, Wei; Yu, Xiyong; Ashraf, Atif; Wary, Kishore K; Xu, Meifeng; Millard, Ronald W; Ashraf, Muhammad; Wang, Yigang 2012. Suicide gene reveals the myocardial neovascularization role of mesenchymal stem cells overexpressing CXCR4 (MSC(CXCR4)). PloS one, 7 9, e46158

Yu, Xi-Yong; Geng, Yong-Jian; Liang, Jia-Liang; Zhang, Saidan; Lei, He-Ping; Zhong, Shi-Long; Lin, Qiu-Xiong; Shan, Zhi-Xin; Lin, Shu-Guang; Li, Yangxin 2012. High levels of glucose induce "metabolic memory" in cardiomyocyte via epigenetic histone H3 lysine 9 methylation. Molecular biology reports, 39 9, 8891-8

Liang, Jia-Liang; Feng, Zhi-Kuan; Liu, Xiao-Ying; Lin, Qiu-Xiong; Fu, Yong-Heng; Shan, Zhi-Xin; Zhu, Jie-Ning; Lin, Shu-Guang; Yu, Xi-Yong 2011. Effect of impaired glucose tolerance on cardiac dysfunction in a rat model of prediabetes. Chinese medical journal, 124 5, 734-9

Yu, Xi-Yong; Chen, Hong-Mei; Liang, Jia-Liang; Lin, Qiu-Xiong; Tan, Hong-Hong; Fu, Yong-Heng; Liu, Xiao-Ying; Shan, Zhi-Xin; Li, Xiao-Hong; Yang, Hua-Zhang; Yang, Min; Li, Yangxin; Lin, Shu-Guang 2011. Hyperglycemic myocardial damage is mediated by proinflammatory cytokine: macrophage migration inhibitory factor. PloS one, 6 1, e16239

Liang, Jia-Liang; Xiao, Ding-Zhang; Liu, Xiao-Ying; Lin, Qiu-Xiong; Shan, Zhi-Xin; Zhu, Jie-Ning; Lin, Shu-Guang; Yu, Xi-Yong 2010. High glucose induces apoptosis in AC16 human cardiomyocytes via macrophage migration inhibitory factor and c-Jun N-terminal kinase. Clinical and experimental pharmacology & physiology, 37 10, 969-73

Yu, Xi-Yong; Geng, Yong-Jian; Liang, Jia-Liang; Lin, Qiu-Xiong; Lin, Shu-Guang; Zhang, Saidan; Li, Yangxin 2010. High levels of glucose induce apoptosis in cardiomyocyte via epigenetic regulation of the insulin-like growth factor receptor. Experimental cell research, 316 17, 2903-9